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Competition between crystal and fibril formation in molecular mutations of amyloidogenic peptides

Amyloidogenic model peptides are invaluable for investigating assembly mechanisms in disease related amyloids and in protein folding. During aggregation, such peptides can undergo bifurcation leading to fibrils or crystals, however the mechanisms of fibril-to-crystal conversion are unclear. We navig...

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Detalles Bibliográficos
Autores principales: Reynolds, Nicholas P., Adamcik, Jozef, Berryman, Joshua T., Handschin, Stephan, Zanjani, Ali Asghar Hakami, Li, Wen, Liu, Kun, Zhang, Afang, Mezzenga, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673901/
https://www.ncbi.nlm.nih.gov/pubmed/29109399
http://dx.doi.org/10.1038/s41467-017-01424-4