Machine learning model for sequence-driven DNA G-quadruplex formation

We describe a sequence-based computational model to predict DNA G-quadruplex (G4) formation. The model was developed using large-scale machine learning from an extensive experimental G4-formation dataset, recently obtained for the human genome via G4-seq methodology. Our model differentiates many wi...

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Detalles Bibliográficos
Autores principales: Sahakyan, Aleksandr B., Chambers, Vicki S., Marsico, Giovanni, Santner, Tobias, Di Antonio, Marco, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673958/
https://www.ncbi.nlm.nih.gov/pubmed/29109402
http://dx.doi.org/10.1038/s41598-017-14017-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673958/
https://www.ncbi.nlm.nih.gov/pubmed/29109402
http://dx.doi.org/10.1038/s41598-017-14017-4

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