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Natural history of Helicobacter pylori VacA toxin in human gastric epithelium in vivo: vacuoles and beyond

Uptake, intracellular trafficking and pathologic effects of VacA toxin from Helicobacter pylori have been widely investigated in vitro. However, no systematic analysis investigated VacA intracellular distribution and fate in H. pylori-infected human gastric epithelium in vivo, using ultrastructural...

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Detalles Bibliográficos
Autores principales: Necchi, Vittorio, Sommi, Patrizia, Vanoli, Alessandro, Fiocca, Roberto, Ricci, Vittorio, Solcia, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673961/
https://www.ncbi.nlm.nih.gov/pubmed/29109534
http://dx.doi.org/10.1038/s41598-017-15204-z