A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing

Liver chips have been developed to recapitulate in vivo physiological conditions to enhance hepatocyte functions for assessing acute responses to drugs. To develop liver chips that can assess repeated dosing chronic hepatotoxicity, we need to ensure that hepatocyte functions be maintained at constan...

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Detalles Bibliográficos
Autores principales: Yu, Fang, Deng, Rensheng, Hao Tong, Wen, Huan, Li, Chan Way, Ng, IslamBadhan, Anik, Iliescu, Ciprian, Yu, Hanry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673965/
https://www.ncbi.nlm.nih.gov/pubmed/29109520
http://dx.doi.org/10.1038/s41598-017-13848-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673965/
https://www.ncbi.nlm.nih.gov/pubmed/29109520
http://dx.doi.org/10.1038/s41598-017-13848-5

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