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A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing
Liver chips have been developed to recapitulate in vivo physiological conditions to enhance hepatocyte functions for assessing acute responses to drugs. To develop liver chips that can assess repeated dosing chronic hepatotoxicity, we need to ensure that hepatocyte functions be maintained at constan...
Autores principales: | Yu, Fang, Deng, Rensheng, Hao Tong, Wen, Huan, Li, Chan Way, Ng, IslamBadhan, Anik, Iliescu, Ciprian, Yu, Hanry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673965/ https://www.ncbi.nlm.nih.gov/pubmed/29109520 http://dx.doi.org/10.1038/s41598-017-13848-5 |
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