Transcriptomic profiling in human mesangial cells using patient-derived lupus autoantibodies identified miR-10a as a potential regulator of IL8

Autoantibody-mediated inflammation directed at resident kidney cells mediates lupus nephritis (LN) pathogenesis. This study investigated the role of miRNA in human mesangial cells (HMCs) stimulated with auto anti-dsDNA immunoglobulin (Ig)G antibodies. HMCs were treated with antibodies purified from...

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Detalles Bibliográficos
Autores principales: Tangtanatakul, Pattarin, Thammasate, Boonyakiat, Jacquet, Alain, Reantragoon, Rangsima, Pisitkun, Trairak, Avihingsanon, Yingyos, Leelahavanichkul, Asada, Hirankarn, Nattiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673966/
https://www.ncbi.nlm.nih.gov/pubmed/29109423
http://dx.doi.org/10.1038/s41598-017-15160-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673966/
https://www.ncbi.nlm.nih.gov/pubmed/29109423
http://dx.doi.org/10.1038/s41598-017-15160-8

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