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SIM2l attenuates resistance to hypoxia and tumor growth by transcriptional suppression of HIF1A in uterine cervical squamous cell carcinoma

Despite chemoradiotherapy being one of the most important modalities in advanced cervical cancer, there is a lack of both usable biomarkers to predict treatment outcome and of knowledge about the mechanism of refractoriness to the therapy. Here we identified a transcriptional factor Single-minded ho...

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Detalles Bibliográficos
Autores principales: Nakamura, Kanako, Komatsu, Masayuki, Chiwaki, Fumiko, Takeda, Takashi, Kobayashi, Yusuke, Banno, Kouji, Aoki, Daisuke, Yoshida, Teruhiko, Sasaki, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674005/
https://www.ncbi.nlm.nih.gov/pubmed/29109451
http://dx.doi.org/10.1038/s41598-017-15261-4