Cytotoxicity of Aconitum alkaloid and its interaction with calf thymus DNA by multi-spectroscopic techniques

The cytotoxicities of three aconitum alkaloids- aconitine, hypaconitine and mesaconitine, and their abilities to bind DNA have been explored. Rat myocardial cells H9c2 were treated with aconitum alkaloids and assessed the cytotoxicities by using MTT assay and flow cytometry. Apoptosis was evidenced...

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Detalles Bibliográficos
Autores principales: Liu, Fei, Tan, Xiaoxin, Han, Xu, Li, Xiang, Li, Nan, Kang, Weijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674014/
https://www.ncbi.nlm.nih.gov/pubmed/29109516
http://dx.doi.org/10.1038/s41598-017-15240-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674014/
https://www.ncbi.nlm.nih.gov/pubmed/29109516
http://dx.doi.org/10.1038/s41598-017-15240-9

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