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Modular endolysin of Burkholderia AP3 phage has the largest lysozyme-like catalytic subunit discovered to date and no catalytic aspartate residue

Endolysins are peptidoglycan-degrading enzymes utilized by bacteriophages to release the progeny from bacterial cells. The lytic properties of phage endolysins make them potential antibacterial agents for medical and industrial applications. Here, we present a comprehensive characterization of phage...

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Detalles Bibliográficos
Autores principales: Maciejewska, Barbara, Źrubek, Karol, Espaillat, Akbar, Wiśniewska, Magdalena, Rembacz, Krzysztof P., Cava, Felipe, Dubin, Grzegorz, Drulis-Kawa, Zuzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674055/
https://www.ncbi.nlm.nih.gov/pubmed/29109551
http://dx.doi.org/10.1038/s41598-017-14797-9