Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells

Targeting model antigens (Ags) to Clec9A on DC has been shown to induce, not only cytotoxic T cells, but also high levels of Ab. In fact, Ab responses against immunogenic Ag were effectively generated even in the absence of DC-activating adjuvants. Here we tested if targeting weakly immunogenic puta...

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Detalles Bibliográficos
Autores principales: Park, Hae-Young, Tan, Peck S., Kavishna, Ranmali, Ker, Anna, Lu, Jinhua, Chan, Conrad E. Z., Hanson, Brendon J., MacAry, Paul A., Caminschi, Irina, Shortman, Ken, Alonso, Sylvie, Lahoud, Mireille H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674066/
https://www.ncbi.nlm.nih.gov/pubmed/29263886
http://dx.doi.org/10.1038/s41541-017-0033-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674066/
https://www.ncbi.nlm.nih.gov/pubmed/29263886
http://dx.doi.org/10.1038/s41541-017-0033-5

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