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FMNL2 destabilises COMMD10 to activate NF-κB pathway in invasion and metastasis of colorectal cancer

BACKGROUND: Diaphanous-related formins (DRFs), actin necleator, have been known to participate in the progression of cancer cells. We previously reported that FMNL2 (Formin-like2), a member of DRFs, was a positive regulator in colorectal cancer (CRC) metastasis, yet proteins and pathways required fo...

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Detalles Bibliográficos
Autores principales: Yang, S S, Li, X M, Yang, M, Ren, X L, Hu, J L, Zhu, X H, Wang, F F, Zeng, Z C, Li, J Y, Cheng, Z Q, Liao, W T, Ding, Y Q, Guan, J, Liang, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674093/
https://www.ncbi.nlm.nih.gov/pubmed/28817833
http://dx.doi.org/10.1038/bjc.2017.260