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MDM2 promotes epithelial–mesenchymal transition and metastasis of ovarian cancer SKOV3 cells
BACKGROUND: Metastasis accounts for the most lethal reason for the death of ovarian cancer patients, but remains largely untreated. Epithelial–mesenchymal transition (EMT) is critical for the conversion of early-stage ovarian tumours into metastatic malignancies. Thus the exploration of the signalli...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674096/ https://www.ncbi.nlm.nih.gov/pubmed/28817834 http://dx.doi.org/10.1038/bjc.2017.265 |