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MDM2 promotes epithelial–mesenchymal transition and metastasis of ovarian cancer SKOV3 cells

BACKGROUND: Metastasis accounts for the most lethal reason for the death of ovarian cancer patients, but remains largely untreated. Epithelial–mesenchymal transition (EMT) is critical for the conversion of early-stage ovarian tumours into metastatic malignancies. Thus the exploration of the signalli...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Wang, Dan-Dan, Wu, Ye-Ping, Su, Dan, Zhou, Tian-Yi, Gai, Ren-Hua, Fu, Ying-Ying, Zheng, Lin, He, Qiao-Jun, Zhu, Hong, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674096/
https://www.ncbi.nlm.nih.gov/pubmed/28817834
http://dx.doi.org/10.1038/bjc.2017.265