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Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes

Many bacterial species, including the human pathogen Pseudomonas aeruginosa, employ a mechanism of intercellular communication known as quorum sensing (QS), which is mediated by signalling molecules termed autoinducers. The Pseudomonas Quinolone Signal (PQS) and 2-Heptyl-3H-4-Quinolone (HHQ) are aut...

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Detalles Bibliográficos
Autores principales: Baker, Y. R., Hodgkinson, J. T., Florea, B. I., Alza, E., Galloway, W. R. J. D., Grimm, L., Geddis, S. M., Overkleeft, H. S., Welch, M., Spring, D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674140/
https://www.ncbi.nlm.nih.gov/pubmed/29163891
http://dx.doi.org/10.1039/c7sc01270e