Preferential targeting of i-motifs and G-quadruplexes by small molecules

i-Motifs and G-quadruplexes are dynamic nucleic acid secondary structures, which are believed to play key roles in gene expression. We herein report two peptidomimetic ligands (PBP1 and PBP2) that selectively target i-motifs and G-quadruplexes over double-stranded DNA. These peptidomimetics, regiois...

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Detalles Bibliográficos
Autores principales: Debnath, Manish, Ghosh, Shirsendu, Chauhan, Ajay, Paul, Rakesh, Bhattacharyya, Kankan, Dash, Jyotirmayee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674183/
https://www.ncbi.nlm.nih.gov/pubmed/29163897
http://dx.doi.org/10.1039/c7sc02693e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674183/
https://www.ncbi.nlm.nih.gov/pubmed/29163897
http://dx.doi.org/10.1039/c7sc02693e

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