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Preferential targeting of i-motifs and G-quadruplexes by small molecules

i-Motifs and G-quadruplexes are dynamic nucleic acid secondary structures, which are believed to play key roles in gene expression. We herein report two peptidomimetic ligands (PBP1 and PBP2) that selectively target i-motifs and G-quadruplexes over double-stranded DNA. These peptidomimetics, regiois...

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Detalles Bibliográficos
Autores principales:	Debnath, Manish, Ghosh, Shirsendu, Chauhan, Ajay, Paul, Rakesh, Bhattacharyya, Kankan, Dash, Jyotirmayee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674183/ https://www.ncbi.nlm.nih.gov/pubmed/29163897 http://dx.doi.org/10.1039/c7sc02693e

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