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Harnessing fungal nonribosomal cyclodepsipeptide synthetases for mechanistic insights and tailored engineering

Nonribosomal peptide synthetases represent potential platforms for the design and engineering of structurally complex peptides. While previous focus has been centred mainly on bacterial systems, fungal synthetases assembling drugs like the antifungal echinocandins, the antibacterial cephalosporins o...

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Detalles Bibliográficos
Autores principales: Steiniger, Charlotte, Hoffmann, Sylvester, Mainz, Andi, Kaiser, Marcel, Voigt, Kerstin, Meyer, Vera, Süssmuth, Roderich D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674221/
https://www.ncbi.nlm.nih.gov/pubmed/29163920
http://dx.doi.org/10.1039/c7sc03093b