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Harnessing fungal nonribosomal cyclodepsipeptide synthetases for mechanistic insights and tailored engineering
Nonribosomal peptide synthetases represent potential platforms for the design and engineering of structurally complex peptides. While previous focus has been centred mainly on bacterial systems, fungal synthetases assembling drugs like the antifungal echinocandins, the antibacterial cephalosporins o...
Autores principales: | Steiniger, Charlotte, Hoffmann, Sylvester, Mainz, Andi, Kaiser, Marcel, Voigt, Kerstin, Meyer, Vera, Süssmuth, Roderich D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674221/ https://www.ncbi.nlm.nih.gov/pubmed/29163920 http://dx.doi.org/10.1039/c7sc03093b |
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