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Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging

As CD13 is selectively expressed in angiogenesis, it can serve as a target for molecular imaging tracers to noninvasively visualize angiogenic processes in vivo. The CD13-targeting moiety NGR was synthesized and cyclized by native chemical ligation (NCL) instead of disulfide bridging, leading to a c...

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Detalles Bibliográficos
Autores principales: Hendrikx, Geert, Hackeng, Tilman M., van Gorp, Rick, Bauwens, Matthias, Schurgers, Leon J., Mottaghy, Felix M., Post, Mark J., Dijkgraaf, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674494/
https://www.ncbi.nlm.nih.gov/pubmed/29204107
http://dx.doi.org/10.1155/2017/8638549