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Abnormal subchondral bone remodeling and its association with articular cartilage degradation in knees of type 2 diabetes patients

Type 2 diabetes (T2D) is associated with systemic abnormal bone remodeling and bone loss. Meanwhile, abnormal subchondral bone remodeling induces cartilage degradation, resulting in osteoarthritis (OA). Accordingly, we investigated alterations in subchondral bone remodeling, microstructure and stren...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Huang, Yong-Can, Yan, Chun Hoi, Chiu, Kwong Yuen, Wei, Qingjun, Zhao, Jingmin, Guo, X Edward, Leung, Frankie, Lu, William W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674679/
https://www.ncbi.nlm.nih.gov/pubmed/29134132
http://dx.doi.org/10.1038/boneres.2017.34