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f-scLVM: scalable and versatile factor analysis for single-cell RNA-seq

Single-cell RNA-sequencing (scRNA-seq) allows studying heterogeneity in gene expression in large cell populations. Such heterogeneity can arise due to technical or biological factors, making decomposing sources of variation difficult. We here describe f-scLVM (factorial single-cell latent variable m...

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Detalles Bibliográficos
Autores principales: Buettner, Florian, Pratanwanich, Naruemon, McCarthy, Davis J., Marioni, John C., Stegle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674756/
https://www.ncbi.nlm.nih.gov/pubmed/29115968
http://dx.doi.org/10.1186/s13059-017-1334-8