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The nonstructural proteins of Pneumoviruses are remarkably distinct in substrate diversity and specificity

BACKGROUND: Interferon (IFN) inhibits viruses by inducing several hundred cellular genes, aptly named ‘interferon (IFN)-stimulated genes’ (ISGs). The only two RNA viruses of the Pneumovirus genus of the Paramyxoviridae family, namely Respiratory Syncytial Virus (RSV) and Pneumonia Virus of Mice (PVM...

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Detalles Bibliográficos
Autores principales: Ribaudo, Michael, Barik, Sailen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674761/
https://www.ncbi.nlm.nih.gov/pubmed/29110727
http://dx.doi.org/10.1186/s12985-017-0881-7