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Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension

Sodium accumulates in the interstitium and promotes inflammation through poorly defined mechanisms. We describe a pathway by which sodium enters dendritic cells (DCs) through amiloride-sensitive channels including the alpha and gamma subunits of the epithelial sodium channel and the sodium hydrogen...

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Detalles Bibliográficos
Autores principales: Barbaro, Natalia R., Foss, Jason D., Kryshtal, Dmytro O., Tsyba, Nikita, Kumaresan, Shivani, Xiao, Liang, Mernaugh, Raymond L., Itani, Hana A., Loperena, Roxana, Chen, Wei, Dikalov, Sergey, Titze, Jens M., Knollmann, Bjorn C., Harrison, David G., Kirabo, Annet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674815/
https://www.ncbi.nlm.nih.gov/pubmed/29069584
http://dx.doi.org/10.1016/j.celrep.2017.10.002