Cargando…
Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension
Sodium accumulates in the interstitium and promotes inflammation through poorly defined mechanisms. We describe a pathway by which sodium enters dendritic cells (DCs) through amiloride-sensitive channels including the alpha and gamma subunits of the epithelial sodium channel and the sodium hydrogen...
Autores principales: | Barbaro, Natalia R., Foss, Jason D., Kryshtal, Dmytro O., Tsyba, Nikita, Kumaresan, Shivani, Xiao, Liang, Mernaugh, Raymond L., Itani, Hana A., Loperena, Roxana, Chen, Wei, Dikalov, Sergey, Titze, Jens M., Knollmann, Bjorn C., Harrison, David G., Kirabo, Annet |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674815/ https://www.ncbi.nlm.nih.gov/pubmed/29069584 http://dx.doi.org/10.1016/j.celrep.2017.10.002 |
Ejemplares similares
-
Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation
por: Ruggeri Barbaro, Natalia, et al.
Publicado: (2020) -
Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs
por: Vu, Kiem, et al.
Publicado: (2023) -
Amiloride: A review
por: Sun, Qianhui, et al.
Publicado: (2020) -
Amiloride-Sensitive Sodium Channels and Pulmonary Edema
por: Althaus, Mike, et al.
Publicado: (2011) -
Epithelial Sodium Channel Inhibition by Amiloride Addressed with THz Spectroscopy and Molecular Modeling
por: Mernea, Maria, et al.
Publicado: (2022)