Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis

BACKGROUND: Macrophages play a pivotal role in atherosclerotic plaque development. Recent evidence has suggested the glucagon-like peptide-1 receptor (GLP-1R) agonist, liraglutide, can attenuate pro-inflammatory responses in macrophages. We hypothesized that liraglutide could limit atherosclerosis p...

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Detalles Bibliográficos
Autores principales: Bruen, Robyn, Curley, Sean, Kajani, Sarina, Crean, Daniel, O’Reilly, Marcella E., Lucitt, Margaret B., Godson, Catherine G., McGillicuddy, Fiona C., Belton, Orina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674826/
https://www.ncbi.nlm.nih.gov/pubmed/29110715
http://dx.doi.org/10.1186/s12933-017-0626-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674826/
https://www.ncbi.nlm.nih.gov/pubmed/29110715
http://dx.doi.org/10.1186/s12933-017-0626-3

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