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Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis

BACKGROUND: Macrophages play a pivotal role in atherosclerotic plaque development. Recent evidence has suggested the glucagon-like peptide-1 receptor (GLP-1R) agonist, liraglutide, can attenuate pro-inflammatory responses in macrophages. We hypothesized that liraglutide could limit atherosclerosis p...

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Detalles Bibliográficos
Autores principales:	Bruen, Robyn, Curley, Sean, Kajani, Sarina, Crean, Daniel, O’Reilly, Marcella E., Lucitt, Margaret B., Godson, Catherine G., McGillicuddy, Fiona C., Belton, Orina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674826/ https://www.ncbi.nlm.nih.gov/pubmed/29110715 http://dx.doi.org/10.1186/s12933-017-0626-3

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