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Co-expression of 1α-hydroxylase and vitamin D receptor in human articular chondrocytes

BACKGROUND: The aim was to investigate whether resident chondrocytes in human articular cartilage and in subculture express vitamin D receptor (VDR) and the enzyme that hydroxylates the prohormone 25(OH)D(3) to the active hormone 1α,25(OH)(2)D(3), namely 1α-hydroxylase (CYP27B1). Any putative effect...

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Detalles Bibliográficos
Autores principales: Hansen, Ann Kristin, Figenschau, Yngve, Zubiaurre-Martinez, Inigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674837/
https://www.ncbi.nlm.nih.gov/pubmed/29110708
http://dx.doi.org/10.1186/s12891-017-1791-y