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Cell–cell adhesion accounts for the different orientation of columnar and hepatocytic cell divisions
Mitotic spindle alignment with the basal or substrate-contacting domain ensures that dividing epithelial cells remain in the plane of the monolayer. Spindle orientation with respect to the substratum is established in metaphase coincident with maximal cell rounding, which enables unobstructed spindl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674875/ https://www.ncbi.nlm.nih.gov/pubmed/28887437 http://dx.doi.org/10.1083/jcb.201608065 |