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Microtubule stabilization drives 3D centrosome migration to initiate primary ciliogenesis

Primary cilia are sensory organelles located at the cell surface. Their assembly is primed by centrosome migration to the apical surface, yet surprisingly little is known about this initiating step. To gain insight into the mechanisms driving centrosome migration, we exploited the reproducibility of...

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Detalles Bibliográficos
Autores principales: Pitaval, Amandine, Senger, Fabrice, Letort, Gaëlle, Gidrol, Xavier, Guyon, Laurent, Sillibourne, James, Théry, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674878/
https://www.ncbi.nlm.nih.gov/pubmed/28993469
http://dx.doi.org/10.1083/jcb.201610039