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­­­Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia­­

A propensity for rewiring genetic and epigenetic regulatory networks, thus enabling sustained cell proliferation, suppression of apoptosis, and the ability to evade the immune system, is vital to cancer cell propagation. An increased understanding of how this is achieved is critical for identifying...

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Detalles Bibliográficos
Autores principales: Cuellar, Trinna L., Herzner, Anna-Maria, Zhang, Xiaotian, Goyal, Yogesh, Watanabe, Colin, Friedman, Brad A., Janakiraman, Vasantharajan, Durinck, Steffen, Stinson, Jeremy, Arnott, David, Cheung, Tommy K., Chaudhuri, Subhra, Modrusan, Zora, Doerr, Jonas Martin, Classon, Marie, Haley, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674883/
https://www.ncbi.nlm.nih.gov/pubmed/28887438
http://dx.doi.org/10.1083/jcb.201612160