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Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia
A propensity for rewiring genetic and epigenetic regulatory networks, thus enabling sustained cell proliferation, suppression of apoptosis, and the ability to evade the immune system, is vital to cancer cell propagation. An increased understanding of how this is achieved is critical for identifying...
Autores principales: | Cuellar, Trinna L., Herzner, Anna-Maria, Zhang, Xiaotian, Goyal, Yogesh, Watanabe, Colin, Friedman, Brad A., Janakiraman, Vasantharajan, Durinck, Steffen, Stinson, Jeremy, Arnott, David, Cheung, Tommy K., Chaudhuri, Subhra, Modrusan, Zora, Doerr, Jonas Martin, Classon, Marie, Haley, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674883/ https://www.ncbi.nlm.nih.gov/pubmed/28887438 http://dx.doi.org/10.1083/jcb.201612160 |
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