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Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly

Cancer-associated fibroblasts (CAFs) are the most abundant cells of the tumor stroma. Their capacity to contract the matrix and induce invasion of cancer cells has been well documented. However, it is not clear whether CAFs remodel the matrix by other means, such as degradation, matrix deposition, o...

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Detalles Bibliográficos
Autores principales: Attieh, Youmna, Clark, Andrew G., Grass, Carina, Richon, Sophie, Pocard, Marc, Mariani, Pascale, Elkhatib, Nadia, Betz, Timo, Gurchenkov, Basile, Vignjevic, Danijela Matic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674886/
https://www.ncbi.nlm.nih.gov/pubmed/28931556
http://dx.doi.org/10.1083/jcb.201702033