Karyopherins regulate nuclear pore complex barrier and transport function

Nucleocytoplasmic transport is sustained by karyopherins (Kaps) and a Ran guanosine triphosphate (RanGTP) gradient that imports nuclear localization signal (NLS)–specific cargoes (NLS-cargoes) into the nucleus. However, how nuclear pore complex (NPC) barrier selectivity, Kap traffic, and NLS-cargo r...

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Detalles Bibliográficos
Autores principales: Kapinos, Larisa E., Huang, Binlu, Rencurel, Chantal, Lim, Roderick Y.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674887/
https://www.ncbi.nlm.nih.gov/pubmed/28864541
http://dx.doi.org/10.1083/jcb.201702092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674887/
https://www.ncbi.nlm.nih.gov/pubmed/28864541
http://dx.doi.org/10.1083/jcb.201702092

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