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Karyopherins regulate nuclear pore complex barrier and transport function

Nucleocytoplasmic transport is sustained by karyopherins (Kaps) and a Ran guanosine triphosphate (RanGTP) gradient that imports nuclear localization signal (NLS)–specific cargoes (NLS-cargoes) into the nucleus. However, how nuclear pore complex (NPC) barrier selectivity, Kap traffic, and NLS-cargo r...

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Detalles Bibliográficos
Autores principales:	Kapinos, Larisa E., Huang, Binlu, Rencurel, Chantal, Lim, Roderick Y.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674887/ https://www.ncbi.nlm.nih.gov/pubmed/28864541 http://dx.doi.org/10.1083/jcb.201702092

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