A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display

ABTAG is a camelid single-domain antibody (sdAb) that binds to bovine serum albumin (BSA) with low picomolar affinity. In surface plasmon resonance (SPR) analyses using BSA surfaces, bound ABTAG can be completely dissociated from the BSA surfaces at low pH, over multiple cycles, without any reductio...

Descripción completa

Detalles Bibliográficos
Autores principales: Hussack, Greg, Baral, Toya Nath, Baardsnes, Jason, van Faassen, Henk, Raphael, Shalini, Henry, Kevin A., Zhang, Jianbing, MacKenzie, C. Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674936/
https://www.ncbi.nlm.nih.gov/pubmed/29163485
http://dx.doi.org/10.3389/fimmu.2017.01406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674936/
https://www.ncbi.nlm.nih.gov/pubmed/29163485
http://dx.doi.org/10.3389/fimmu.2017.01406

Ejemplares similares