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STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade

Signal transducer and activator of transcription 1 (STAT1) mediates interferon gamma signaling which activates the expression of various genes related to apoptosis, inflammation, cell cycle and angiogenesis. Several experimental and clinical studies have investigated the role of STAT1 in primary tum...

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Detalles Bibliográficos
Autores principales: Varikuti, Sanjay, Oghumu, Steve, Elbaz, Mohamad, Volpedo, Greta, Ahirwar, Dinesh K., Alarcon, Pablo C., Sperling, Rachel H., Moretti, Ellen, Pioso, Marissa S., Kimble, Jennifer, Nasser, Mohd W., Ganju, Ramesh K., Terrazas, Cesar, Satoskar, Abhay R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674966/
https://www.ncbi.nlm.nih.gov/pubmed/29147627
http://dx.doi.org/10.1080/2162402X.2017.1361088