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STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade
Signal transducer and activator of transcription 1 (STAT1) mediates interferon gamma signaling which activates the expression of various genes related to apoptosis, inflammation, cell cycle and angiogenesis. Several experimental and clinical studies have investigated the role of STAT1 in primary tum...
Autores principales: | Varikuti, Sanjay, Oghumu, Steve, Elbaz, Mohamad, Volpedo, Greta, Ahirwar, Dinesh K., Alarcon, Pablo C., Sperling, Rachel H., Moretti, Ellen, Pioso, Marissa S., Kimble, Jennifer, Nasser, Mohd W., Ganju, Ramesh K., Terrazas, Cesar, Satoskar, Abhay R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674966/ https://www.ncbi.nlm.nih.gov/pubmed/29147627 http://dx.doi.org/10.1080/2162402X.2017.1361088 |
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