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Targeting HPV‐infected cervical cancer cells with PEGylated liposomes encapsulating siRNA and the role of siRNA complexation with polyethylenimine

The greatest obstacle to clinical application of cancer gene therapy is lack of effective delivery tools. Gene delivery vehicles must protect against degradation, avoid immunogenic effects and prevent off target delivery which can cause harmful side effects. PEGylated liposomes have greatly improved...

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Detalles Bibliográficos
Autores principales: Levine, Rachel M., Dinh, Christina V., Harris, Michael A., Kokkoli, Efrosini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675078/
https://www.ncbi.nlm.nih.gov/pubmed/29313012
http://dx.doi.org/10.1002/btm2.10022