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Poly(2‐propylacrylic acid)/poly(lactic‐co‐glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4(+) or CD8(+) T cell activation

Poly(lactic‐co‐glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner. Micron‐sized PLGA MPs are readily phagocytosed by antigen presenting cel...

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Detalles Bibliográficos
Autores principales: Yang, Lirong, Bracho‐Sanchez, Evelyn, Fernando, Lawrence P., Lewis, Jamal S., Carstens, Matthew R., Duvall, Craig L., Keselowsky, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675098/
https://www.ncbi.nlm.nih.gov/pubmed/29313030
http://dx.doi.org/10.1002/btm2.10068