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Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7R(pos) long-term memory phenotype is associated with protection from vertical transmission

Congenital human cytomegalovirus (HCMV) infection is the major cause of birth defects and a precise definition of the HCMV-specific T-cell response in primary infection may help define reliable correlates of immune protection during pregnancy. In this study, a high throughput method was used to defi...

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Detalles Bibliográficos
Autores principales: Mele, Federico, Fornara, Chiara, Jarrossay, David, Furione, Milena, Arossa, Alessia, Spinillo, Arsenio, Lanzavecchia, Antonio, Gerna, Giuseppe, Sallusto, Federica, Lilleri, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675411/
https://www.ncbi.nlm.nih.gov/pubmed/29112951
http://dx.doi.org/10.1371/journal.pone.0187731