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Prediction of drug cocktail effects when the number of measurements is limited

Cocktails of drugs can be more effective than single drugs, because they can potentially work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails drawn from a large set of drugs because of the huge number of combinations. To overcome this combinatorial explosion...

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Detalles Bibliográficos
Autores principales: Zimmer, Anat, Tendler, Avichai, Katzir, Itay, Mayo, Avi, Alon, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675459/
https://www.ncbi.nlm.nih.gov/pubmed/29073201
http://dx.doi.org/10.1371/journal.pbio.2002518