Acquisition of an oncogenic fusion protein is sufficient to globally alter the landscape of miRNA expression to inhibit myogenic differentiation

The differentiation status of tumors is used as a prognostic indicator, with tumors comprised of less differentiated cells exhibiting higher levels of aggressiveness that correlate with a poor prognosis. Although oncogenes contribute to blocking differentiation, it is not clear how they globally alt...

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Detalles Bibliográficos
Autores principales: Loupe, Jacob M., Miller, Patrick J., Crabtree, Judy S., Zabaleta, Jovanny, Hollenbach, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675615/
https://www.ncbi.nlm.nih.gov/pubmed/29152063
http://dx.doi.org/10.18632/oncotarget.19693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675615/
https://www.ncbi.nlm.nih.gov/pubmed/29152063
http://dx.doi.org/10.18632/oncotarget.19693

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