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Kahweol decreases hepatic fibrosis by inhibiting the expression of connective tissue growth factor via the transforming growth factor-beta signaling pathway

Kahweol is a diterpene molecule found in Coffea Arabica beans. Previous studies have shown that coffee reduces liver fibrosis, but it is not clear which component of coffee has the protective effect. In this study, we examined whether kahweol has a protective effect on hepatic fibrosis in vivo and i...

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Detalles Bibliográficos
Autores principales: Seo, Hye-Young, Jung, Yun-A, Lee, So-Hee, Hwang, Jae Seok, Park, Keun-Gyu, Kim, Mi-Kyung, Jang, Byoung Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675617/
https://www.ncbi.nlm.nih.gov/pubmed/29152065
http://dx.doi.org/10.18632/oncotarget.19756