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Platelet derived TGF-β promotes cervical carcinoma cell growth by suppressing KLF6 expression

Platelets in the primary tumor microenvironment play crucial roles in regulating tumor growth, metastasis, and angiogenesis, but the underlying mechanisms are unclear. Here, we show that platelet releasates exhibited a proliferative effect on HeLa cells, and this effect correlated with a reduction o...

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Detalles Bibliográficos
Autores principales: He, Ao-Di, Wang, Shao-Ping, Xie, Wen, Song, Wei, Miao, Shuo, Yang, Ru-Ping, Zhu, Ying, Xiang, Ji-Zhou, Ming, Zhang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675624/
https://www.ncbi.nlm.nih.gov/pubmed/29152072
http://dx.doi.org/10.18632/oncotarget.19912