The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients

Breakage of the fragile site FRA16D disrupts the WWOX (WW Domain Containing Oxidoreductase) tumor suppressor gene in osteosarcoma. However, the frequency of breakage is not sufficient to explain the rate of WWOX loss in pathogenesis. The involvement of non-coding RNA transcripts is proposed due to t...

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Detalles Bibliográficos
Autores principales: O'Leary, Valerie Bríd, Maugg, Doris, Smida, Jan, Baumhoer, Daniel, Nathrath, Michaela, Ovsepian, Saak Victor, Atkinson, Michael John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675644/
https://www.ncbi.nlm.nih.gov/pubmed/29152092
http://dx.doi.org/10.18632/oncotarget.21086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675644/
https://www.ncbi.nlm.nih.gov/pubmed/29152092
http://dx.doi.org/10.18632/oncotarget.21086

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