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The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients
Breakage of the fragile site FRA16D disrupts the WWOX (WW Domain Containing Oxidoreductase) tumor suppressor gene in osteosarcoma. However, the frequency of breakage is not sufficient to explain the rate of WWOX loss in pathogenesis. The involvement of non-coding RNA transcripts is proposed due to t...
Autores principales: | O'Leary, Valerie Bríd, Maugg, Doris, Smida, Jan, Baumhoer, Daniel, Nathrath, Michaela, Ovsepian, Saak Victor, Atkinson, Michael John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675644/ https://www.ncbi.nlm.nih.gov/pubmed/29152092 http://dx.doi.org/10.18632/oncotarget.21086 |
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