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Functional network analysis of gene-phenotype connectivity associated with temozolomide

RATIONALE: Glioma has a poor survival rate in patients even with aggressive treatment. Temozolomide (TMZ) is the standard chemotherapeutic choice for treating glioma, but TMZ treatment consistently leads to high resistance. AIM: To investigate the underlying mechanisms of TMZ action with new therape...

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Detalles Bibliográficos
Autores principales: Shi, Jia, Dong, Bo, Zhou, Peng, Guan, Wei, Peng, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675653/
https://www.ncbi.nlm.nih.gov/pubmed/29152101
http://dx.doi.org/10.18632/oncotarget.20848