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Longitudinal evaluation of myocardial glucose metabolism and contractile function in obese type 2 diabetic db/db mice using small-animal dynamic (18)F-FDG PET and echocardiography
The aim was to evaluate sequential changes of myocardial glucose utilization and LV systolic function in db/db mice. Eight db/db and eight wild-type mice underwent plasma substrate analysis and dynamic (18)F-FDG PET at week 8 (W8), W10, W12, W14, and W16. (18)F-FDG uptake constant Ki and the rate of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675673/ https://www.ncbi.nlm.nih.gov/pubmed/29152121 http://dx.doi.org/10.18632/oncotarget.21202 |