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Modulation of cabozantinib efficacy by the prostate tumor microenvironment

The tumor microenvironment (TME) is increasingly recognized as the arbiter of metastatic progression and drug resistance in advanced prostate cancer (PCa). Cabozantinib is a potent tyrosine kinase inhibitor (TKI) with reported biological activity in the PCa epithelia, but failed to provide an overal...

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Detalles Bibliográficos
Autores principales: Tripathi, Manisha, Nandana, Srinivas, Billet, Sandrine, Cavassani, Karen A., Mishra, Rajeev, Chung, Leland W.K., Posadas, Edwin M., Bhowmick, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675680/
https://www.ncbi.nlm.nih.gov/pubmed/29152128
http://dx.doi.org/10.18632/oncotarget.21248