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Postnatal calpain inhibition elicits cerebellar cell death and motor dysfunction

Calpain-1 deletion elicits neurodevelopmental disorders, such as ataxia. However, the function of calpain in postnatal neurodevelopment and its mechanisms remain unknown. In this study, we revealed that postnatal intraperitoneal injection of various calpain inhibitors attenuated cerebellar cytosolic...

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Detalles Bibliográficos
Autores principales: Li, Junyao, Yang, Sanjuan, Zhu, Guoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675688/
https://www.ncbi.nlm.nih.gov/pubmed/29152136
http://dx.doi.org/10.18632/oncotarget.21324