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Postnatal calpain inhibition elicits cerebellar cell death and motor dysfunction
Calpain-1 deletion elicits neurodevelopmental disorders, such as ataxia. However, the function of calpain in postnatal neurodevelopment and its mechanisms remain unknown. In this study, we revealed that postnatal intraperitoneal injection of various calpain inhibitors attenuated cerebellar cytosolic...
Autores principales: | Li, Junyao, Yang, Sanjuan, Zhu, Guoqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675688/ https://www.ncbi.nlm.nih.gov/pubmed/29152136 http://dx.doi.org/10.18632/oncotarget.21324 |
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